Before starting your medicine, please read the patient information leaflet that is included in your Xonvea pack.
Doxylamine and pyridoxine can be used to manage the symptoms of Nausea and Vomiting of Pregnancy in women for whom conservative management, like diet and lifestyle changes, has not been successful.
Xonvea is used by pregnant women, to help stop them from feeling sick (nausea) and being sick (vomiting). It is given when changes in diet or other non-medicinal treatments have not worked, such as ginger, acupressure and rest.
Nausea and Vomiting of Pregnancy (NVP), commonly known as morning sickness, is the most common medical condition of pregnancy, affecting up to 80% of all pregnant women.
Typically symptoms start between 4-7 weeks of pregnancy and can occur at any time of the day or night. Up to 20% of women continue to experience nausea, vomiting and retching beyond 20 weeks of pregnancy.
You have been prescribed Xonvea because you have been diagnosed with NVP and changes in diet and other non-medicinal treatments have failed. This can be very unpleasant and may be affecting your day-to-day life.
Xonvea is a tablet formulated to reduce the symptoms of Nausea and Vomiting of Pregnancy. Xonvea contains two medicines called: ‘doxylamine succinate 10mg’ and ‘pyridoxine hydrochloride 10mg’.
Always take this medicine exactly as your doctor, pharmacist or nurse has told you. Check with your doctor, pharmacist or nurse if you are not sure. Continued need for Xonvea should be reassessed as the pregnancy progresses.
Your doctor will start you on a low dose and possibly increase it – this will depend on how well the medicine works for you.
If you take more Xonvea than advised, stop taking Xonvea and talk to a doctor or seek medical advice as soon as possible. Take the medicine pack with you.
You may experience some of the following: feeling restless, sleepy or dizzy, dry mouth, larger black part of the eye (dilated pupils), confusion, fast heart rate.
Do not stop taking Xonvea without talking to your doctor first. If you stop taking this medicine suddenly your feeling sick (nausea), and being sick (vomiting), may come back. Your doctor will advise you on how to stop/ reduce your medication.
Doxylamine and pyridoxine is a medicine combination used in pregnancy and has been prescribed to over 33 million pregnant women worldwide for 40 years. There is no evidence that doxylamine and pyridoxine is associated with an increased risk of birth defects.
However, like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:
Very common side effects (may affect more than 1 in 10 people):
Common (may affect up to 1 in 10 people):
Do not take Xonvea if you are allergic to doxylamine succinate or other antihistamines or if you are taking medicines for depression called ‘monoamine oxidase inhibitors’ (MAOIs).
Talk to your doctor, pharmacist or nurse before taking Xonvea if you have ever had:
Also, talk to your doctor, pharmacist or nurse before taking Xonvea if:
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine. You can also report them to Alliance on +44 (0)1249 466966 or firstname.lastname@example.org
More information about Xonvea (doxylamine and pyridoxine) can be read in the patient information leaflet and summary of product characteristics: